Graduate School on Metal Ions in Biological Systems (MIBS)
Spectroscopic and Kinetic Characterization of Native and Designed Multicopper Oxidases
Department of Natural Sciences in collaboration with Novozymes A/S wishes to appoint a Ph.D. fellow in Spectroscopic and Kinetic Characterization of Native and Designed Multicopper Oxidases from 1 September 2008, or as soon as possible thereafter.
Job description
With reference to the project manager, the work of the Ph.D. fellow will consist mainly of duties in connection with research and development within Bioinorganic chemistry.
The PhD project is focusing on laccases. A kinetic analysis of provided wild-type and mutant laccases will enable establishment of correlations between the screening assays and enzyme kinetics which is essential for laccase optimization and wild-type screening. The project will also focus on the connection between the redox potential and substrate oxidation/electron transfer. Characterization of the Cu centres is crucial to gain insight into the effect of specific mutations on the basic features of the proteins and it will require redox-potential determination, UV-Vis, stopped-flow, CD & EPR measurements, as well as other methods.
The appointed should have experience within one or more of the following areas:
- Spectroscopy on metal ions in model systems and/or in biological systems
- Structure and function of metal ion containing enzymes and proteins
- Inorganic coordination chemistry
Qualification requirements
In connection with the appointment to the post special importance will be attached to the applicant having the professional and personal qualifications stated below:
Familiar with writing and speaking English. KU generally encourages employees who do not speak Danish to acquire a working knowledge of the language.
The Ph.D. fellow is required to have initiative and research potential, to be enterprising and have ability to work as part of a team.
Questions
For further information about the post, please contact professor Morten J. Bjerrum. on tel. (+45) 35 33 24 52
Application
The application should be submitted in 3 copies (sorted); therefore it is not possible to receive the application by e-mail. The application must include a reply e-mail address. Each application must include the following appendices marked with the stated appendix numbers:
- Appendix 1: curriculum vitae with documentation of education.
- Appendix 2: material required for expert assessment.
In addition to the material submitted by the applicant the Assessment Committee may require further material in its assessment of the applicant. In this case it is the responsibility of the applicant, on request, to send the material to the Committee.
Following processing of the application, any application material sent will be destroyed.
Receipt of the application will not be acknowledged, but the applicant will continuously be kept informed of the progress of the application.
The applicant will be assessed according to the Ministry of Science Technology and Innovation Executive Order no. 92 of 15 February 2008.
The application, marked 625-92 should be sent to Cluster of Research Schools - Chemistry & Environment, The Faculty of Life Sciences, Department of Natural Sciences, Thorvaldsensvej 40, DK-1871 Frederiksberg C, where it must be received no later than 1 June 2008 at 12.00 noon. Applications received after the closing date for applications will not be considered.
The Faculty of Life Sciences is one of Europe's leading university environments in the areas of food, health, plants, biotechnology, natural resources, the environment and related academic areas.
Our research and degree programmes are centred on knowledge and tools that can help secure a brighter future for humans, animals and plants.
Read more about The Faculty of Life Sciences at www.life.ku.dk/English
