University of Amsterdam Faculty of Science
Amsterdam, 1098 SM (Noord-Holland), 38 hours per week
Job description
Within the research group Nuclear Organisation Group (Living Cell theme), that will carry out a research project concentrating on hierarchical regulation of gene networks in higher eukaryotes, are vacancies for 3 PhD students (promovendi) for three different projects.
Project
"Gene regulation in higher eukaryotes: A combined approach of quantitative experiments in living cells and mathematical modelling".
Gene regulation relies on a myriad of macromolecular components that jointly orchestrate gene expression that specifies cell adaptation, physiological state and cell type. Research to unravel gene control systems is a main focus in contemporary cell biology particularly since (epi-)genetic control systems are potential drug targets to enable treatment of disease-related gene dysregulation. The three advertised PhD-student projects aim at elucidating principles that govern functioning of (epi-) genetic gene regulation in higher eukaryotes using a systems-biological approach combining experimentation and computational modeling. Project #1 and #2 use experimental cell biology techniques to understand the complex mechanisms of in vivo (epi-)genetic gene control using a combined approach of quantitative experiments in living cells and mathematical modelling. Project #3 uses computational systems biology techniques. The three projects build on extensive expertise in the research groups of Dr. Verschure (UvA) and Dr. Bruggeman (NISB) to investigate (epi-)genetic control of gene expression in mammalian cells by (i) integrating molecular-cell biology technologies and advanced microscopy analysis and (ii) mathematical modeling of key regulatory mechanisms of gene activity.
Requirements
Required education/skills:University Graduate
The candidates should be highly motivated and preferentially have good experience with basic molecular biology techniques, good organization skills and good writing and oral communication skills in English. Candidates for project # 1 and project #2 should have a master's degree in Biochemistry, Cell biology, or Molecular biology (or equivalent) and should be open for mathematical modeling approaches. The candidate for the computational systems biology project should have a master's degree in Systems Biology, Biophysics, or (Bio-) Engineering (or equivalent). The candidates should be willing to work in an interdisciplinary project and institute (Netherlands Institute of Systems Biology).
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Natural Sciences)
Organization
University of Amsterdam
Faculty of Science
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
The Faculty of Science of the University of Amsterdam (UvA) is one of Europe's foremost institutions for higher education and research in its chosen fields of specialization. It plays an active role in international science networks and collaborates with universities and industry. The Faculty has approximately 2000 students and 1500 staff members spread over four departments and ten research institutes. Each institute has its own research programme, a substantial part of which is externally financed by the Netherlands Organization for Scientific Research (NWO), the Dutch government, the EU and various private enterprises.
In 2010, the Faculty will relocate to Science Park Amsterdam. Ambitious building projects are paving the way for this relocation. The move will make the Park one of the largest centres of academic research in the Netherlands
The Swammerdam Institute for Life Sciences (SILS) is one of the Faculty's largest institutes. Within it, approximately 250 scientists and staff members perform excellent research centred on four themes: 1) The Living Cell, 2) Plants and Health, 3) Inside and Beyond the Brain, and 4) Life Science Technologies. Institute members give advanced lectures and courses, while the Institute itself stimulates scientific cooperation between participating groups and colleagues all over the world.
Conditions of employment
Employment basis: Temporary for specified period
Duration of the contract: See below
Maximum hours per week: 38
Additional conditions of employment:
The appointment will be on a temporary basis for a maximum period of four years (18 months plus a further 30 months after a positive evaluation) and should lead to a dissertation (PhD thesis). An educational plan will be drafted that includes attendance of courses and (international) meetings. The PhD student is also expected to assist in teaching of undergraduates.
Based on a full-time appointment (38 hours per week) the gross monthly salary will range from € 2000,- in the first year and € 2558,- in the final year, according to the Dutch salary scales for PhD students.
Additional Information
Additional information about the vacancy can be obtained from:
Dr P.J. Verschure (UvA; project #1 and project #2)
Telephone number: 0031-(0)20-525-5151
E-mail address: P.J.Verschure@uva.nl
Or Dr FJ Bruggeman (NISB; project #3)
E-mail address: frank.bruggeman@cwi.nl
Or additional information can be obtained through one of the following links:
You can apply for this job before 25-06-2008 (dd-mm-yyyy) by sending your application to:
Personnel Department, University of Amsterdam, Faculty of Science
Kruislaan 404
1098 SM Amsterdam
E-mail: application@science.uva.nl
When applying for this job always mention the vacancynumber AT 08-1026.
Job description
Within the research group Nuclear Organisation Group (Living Cell theme), that will carry out a research project concentrating on hierarchical regulation of gene networks in higher eukaryotes, are vacancies for 3 PhD students (promovendi) for three different projects.
Project
"Gene regulation in higher eukaryotes: A combined approach of quantitative experiments in living cells and mathematical modelling".
Gene regulation relies on a myriad of macromolecular components that jointly orchestrate gene expression that specifies cell adaptation, physiological state and cell type. Research to unravel gene control systems is a main focus in contemporary cell biology particularly since (epi-)genetic control systems are potential drug targets to enable treatment of disease-related gene dysregulation. The three advertised PhD-student projects aim at elucidating principles that govern functioning of (epi-) genetic gene regulation in higher eukaryotes using a systems-biological approach combining experimentation and computational modeling. Project #1 and #2 use experimental cell biology techniques to understand the complex mechanisms of in vivo (epi-)genetic gene control using a combined approach of quantitative experiments in living cells and mathematical modelling. Project #3 uses computational systems biology techniques. The three projects build on extensive expertise in the research groups of Dr. Verschure (UvA) and Dr. Bruggeman (NISB) to investigate (epi-)genetic control of gene expression in mammalian cells by (i) integrating molecular-cell biology technologies and advanced microscopy analysis and (ii) mathematical modeling of key regulatory mechanisms of gene activity.
Requirements
Required education/skills:University Graduate
The candidates should be highly motivated and preferentially have good experience with basic molecular biology techniques, good organization skills and good writing and oral communication skills in English. Candidates for project # 1 and project #2 should have a master's degree in Biochemistry, Cell biology, or Molecular biology (or equivalent) and should be open for mathematical modeling approaches. The candidate for the computational systems biology project should have a master's degree in Systems Biology, Biophysics, or (Bio-) Engineering (or equivalent). The candidates should be willing to work in an interdisciplinary project and institute (Netherlands Institute of Systems Biology).
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Natural Sciences)
Organization
University of Amsterdam
Faculty of Science
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
The Faculty of Science of the University of Amsterdam (UvA) is one of Europe's foremost institutions for higher education and research in its chosen fields of specialization. It plays an active role in international science networks and collaborates with universities and industry. The Faculty has approximately 2000 students and 1500 staff members spread over four departments and ten research institutes. Each institute has its own research programme, a substantial part of which is externally financed by the Netherlands Organization for Scientific Research (NWO), the Dutch government, the EU and various private enterprises.
In 2010, the Faculty will relocate to Science Park Amsterdam. Ambitious building projects are paving the way for this relocation. The move will make the Park one of the largest centres of academic research in the Netherlands
The Swammerdam Institute for Life Sciences (SILS) is one of the Faculty's largest institutes. Within it, approximately 250 scientists and staff members perform excellent research centred on four themes: 1) The Living Cell, 2) Plants and Health, 3) Inside and Beyond the Brain, and 4) Life Science Technologies. Institute members give advanced lectures and courses, while the Institute itself stimulates scientific cooperation between participating groups and colleagues all over the world.
Conditions of employment
Employment basis: Temporary for specified period
Duration of the contract: See below
Maximum hours per week: 38
Additional conditions of employment:
The appointment will be on a temporary basis for a maximum period of four years (18 months plus a further 30 months after a positive evaluation) and should lead to a dissertation (PhD thesis). An educational plan will be drafted that includes attendance of courses and (international) meetings. The PhD student is also expected to assist in teaching of undergraduates.
Based on a full-time appointment (38 hours per week) the gross monthly salary will range from € 2000,- in the first year and € 2558,- in the final year, according to the Dutch salary scales for PhD students.
Additional Information
Additional information about the vacancy can be obtained from:
Dr P.J. Verschure (UvA; project #1 and project #2)
Telephone number: 0031-(0)20-525-5151
E-mail address: P.J.Verschure@uva.nl
Or Dr FJ Bruggeman (NISB; project #3)
E-mail address: frank.bruggeman@cwi.nl
Or additional information can be obtained through one of the following links:
- About the organization (http://www.uva.nl/start.cfm/la=en/th=main)
- About the department (http://www.science.uva.nl/english/home.cfm)
- About the function (http://www.uva.nl/vacatures/vacatures.cfm/3A642588-1321-B0BE-A4DA9A20F3740F50)
- Swammerdam Institute for Life Sciences (http://www.science.uva.nl/sils/home.cfm)
You can apply for this job before 25-06-2008 (dd-mm-yyyy) by sending your application to:
Personnel Department, University of Amsterdam, Faculty of Science
Kruislaan 404
1098 SM Amsterdam
E-mail: application@science.uva.nl
When applying for this job always mention the vacancynumber AT 08-1026.
