Radboud University Nijmegen Faculty of Science, Mathematics and Computing Science
Nijmegen, (Gelderland), 40 hours per week
Job description
You will be working in the field of Molecular Neurobiology (including developmental aspects), using in particular molecular, cell-biological, physiological and behavioural research approaches. You will participate in the research programme on the unravelling of the molecular basis of neurodevelopmental psychiatric disorders, in particular the effects of (epi)genetic and environmental (early-life stress) factors on brain development/ behavioural phenotypes. Project in short: A fundamental question in the neurobiology of psychiatric disorders is how the interaction between predisposing genes and a change in environment (e.g. early-life stressors) can produce a phenotype that is vulnerable to a neurodevelopmental disorder, such as schizophrenia. We want to establish the molecular genetic and neurobiological basis of a rat model that displays a complex phenotype remarkably similar to that of patients with schizophrenia. In humans, we are trying to identify susceptibility genes for such disorders. Central question of the project: what programmes the brain for vulnerability to neurodevelopmental psychiatric disorders? Through our studies we hope to highlight the crucial role of neurodevelopmental signalling pathways and stressful (early) life events in programming the brain for vulnerability to these disorders.
Requirements
Required education/skills:University Graduate
Candidates should have obtained an MSc degree in (Medical) Biology, Molecular/Cellular Neurobiology, Molecular Life Sciences or equivalent. Preferably, candidates have some background in Developmental Biology, experience with animal models, and a high affinity for fundamental research related to clinical problems. Relevant experience with animal behavioural research is an advantage.
Job type: Research / Advising
Workfield(s):
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Natural Sciences)
Organization
Radboud University Nijmegen
Faculty of Science, Mathematics and Computing Science
Strategically located in Europe, Radboud University Nijmegen is one of the leading academic communities in the Netherlands. A place with a personal touch, where top-flight education and research take place on a beautiful green campus in modern buildings with state-of-art facilities.
The challenge of the research performed in the Department of Molecular Animal Physiology is to map the brain from genotype to molecular pathways in neurodevelopmental trajectories to neuronal circuitry phenotypes and beyond to behaviour and cognition. The department is part of the Donders Centre for Neuroscience (theme 2: Functional Neurogenomics/Neurodevelopment, in which the roles of [brain] genes and their products are examined, often in [genetically modified] neuronal cells in culture and in [genetically modified] animal models), and affiliated with and housed in the Nijmegen Centre for Molecular Life Sciences (NCMLS; theme 3: Cell growth and differentiation) of Radboud University. Website: www.ru.nl/molanphys/. The Donders Centre for Neuroscience brings together multidisciplinary basic and clinical research groups from the Faculty of Science and the Radboud University Nijmegen Medical Centre. The researchers at the Centre combine basic research on cognitive neuroscience and applied clinical research. Website: www.ru.nl/dcn. The Nijmegen Centre for Molecular Life Sciences (NCMLS) is a leading European research school within the domain of Molecular Mechanisms of Disease, provides an excellent and challenging research environment, and includes departments of the Radboud University Nijmegen Medical Centre. Multidisciplinary research within the NCMLS is also reflected in international MSc and PhD programmes. Website: www.ncmls.eu.
Date of entry: 23/06/2008
Conditions of employment
Maximum salary amount in Euro's a month 2.558
Employment basis: Temporary for specified period
Duration of the contract: The first contract will be for 1.5 years, with possible extension by 2.5 years.
Maximum hours per week: 40
Additional conditions of employment:
The candidate will be appointed as a PhD student for a period of four years. The candidate’s performance will be evaluated after 18 months. If the evaluation is positive, the contract will be extended by 2.5 years.
Additional Information
Additional information about the vacancy can be obtained from:
prof. dr. G.J.M. Martens
Telephone number: 31 (0)24 3610564
E-mail address: g.martens@ncmls.ru.nl
Or additional information can be obtained through one of the following links:
You can apply for this job before 16-08-2008 (dd-mm-yyyy) by sending your application to:
Faculteit der Natuurwetenschappen, Wiskunde en Informatica
RU Nijmegen, afdeling P&O t.a.v. mrs. M. Coppus
Postbus 9010, 6500 GL Nijmegen, NL
E-mail: pz@science.ru.nl
When applying for this job always mention the vacancynumber 62.31.08.
Job description
You will be working in the field of Molecular Neurobiology (including developmental aspects), using in particular molecular, cell-biological, physiological and behavioural research approaches. You will participate in the research programme on the unravelling of the molecular basis of neurodevelopmental psychiatric disorders, in particular the effects of (epi)genetic and environmental (early-life stress) factors on brain development/ behavioural phenotypes. Project in short: A fundamental question in the neurobiology of psychiatric disorders is how the interaction between predisposing genes and a change in environment (e.g. early-life stressors) can produce a phenotype that is vulnerable to a neurodevelopmental disorder, such as schizophrenia. We want to establish the molecular genetic and neurobiological basis of a rat model that displays a complex phenotype remarkably similar to that of patients with schizophrenia. In humans, we are trying to identify susceptibility genes for such disorders. Central question of the project: what programmes the brain for vulnerability to neurodevelopmental psychiatric disorders? Through our studies we hope to highlight the crucial role of neurodevelopmental signalling pathways and stressful (early) life events in programming the brain for vulnerability to these disorders.
Requirements
Required education/skills:University Graduate
Candidates should have obtained an MSc degree in (Medical) Biology, Molecular/Cellular Neurobiology, Molecular Life Sciences or equivalent. Preferably, candidates have some background in Developmental Biology, experience with animal models, and a high affinity for fundamental research related to clinical problems. Relevant experience with animal behavioural research is an advantage.
Job type: Research / Advising
Workfield(s):
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Natural Sciences)
Organization
Radboud University Nijmegen
Faculty of Science, Mathematics and Computing Science
Strategically located in Europe, Radboud University Nijmegen is one of the leading academic communities in the Netherlands. A place with a personal touch, where top-flight education and research take place on a beautiful green campus in modern buildings with state-of-art facilities.
The challenge of the research performed in the Department of Molecular Animal Physiology is to map the brain from genotype to molecular pathways in neurodevelopmental trajectories to neuronal circuitry phenotypes and beyond to behaviour and cognition. The department is part of the Donders Centre for Neuroscience (theme 2: Functional Neurogenomics/Neurodevelopment, in which the roles of [brain] genes and their products are examined, often in [genetically modified] neuronal cells in culture and in [genetically modified] animal models), and affiliated with and housed in the Nijmegen Centre for Molecular Life Sciences (NCMLS; theme 3: Cell growth and differentiation) of Radboud University. Website: www.ru.nl/molanphys/. The Donders Centre for Neuroscience brings together multidisciplinary basic and clinical research groups from the Faculty of Science and the Radboud University Nijmegen Medical Centre. The researchers at the Centre combine basic research on cognitive neuroscience and applied clinical research. Website: www.ru.nl/dcn. The Nijmegen Centre for Molecular Life Sciences (NCMLS) is a leading European research school within the domain of Molecular Mechanisms of Disease, provides an excellent and challenging research environment, and includes departments of the Radboud University Nijmegen Medical Centre. Multidisciplinary research within the NCMLS is also reflected in international MSc and PhD programmes. Website: www.ncmls.eu.
Date of entry: 23/06/2008
Conditions of employment
Maximum salary amount in Euro's a month 2.558
Employment basis: Temporary for specified period
Duration of the contract: The first contract will be for 1.5 years, with possible extension by 2.5 years.
Maximum hours per week: 40
Additional conditions of employment:
The candidate will be appointed as a PhD student for a period of four years. The candidate’s performance will be evaluated after 18 months. If the evaluation is positive, the contract will be extended by 2.5 years.
Additional Information
Additional information about the vacancy can be obtained from:
prof. dr. G.J.M. Martens
Telephone number: 31 (0)24 3610564
E-mail address: g.martens@ncmls.ru.nl
Or additional information can be obtained through one of the following links:
- About the organization (http://www.ru.nl)
- About the department (http://www.ru.nl/dcn)
- About the function (http://www.ru.nl/dcn)
- Radboud University Nijmegen (http://www.ru.nl)
You can apply for this job before 16-08-2008 (dd-mm-yyyy) by sending your application to:
Faculteit der Natuurwetenschappen, Wiskunde en Informatica
RU Nijmegen, afdeling P&O t.a.v. mrs. M. Coppus
Postbus 9010, 6500 GL Nijmegen, NL
E-mail: pz@science.ru.nl
When applying for this job always mention the vacancynumber 62.31.08.
