Leiden University Medical Centre the division of Drug Delivery Technolgy
Leiden, 2300 RA (The Netherlands), 38 hours per week
Job description
Function title: Ph.D. Student
For a project entitled: "Improved delivery systems for efficacious peptide-based vaccines for immunotherapy of cancer"
The project
The Division of Drug Delivery Technology of the Leiden/Amsterdam center for Drug Research (LACDR), Leiden University and the Department of Clinical Pharmacy & Toxicology of the Leiden University Medical Center (LUMC) are joined together in an ambitious project to further develop vaccine-based immunotherapy of cancer.
Vaccination with synthetic peptides covering MHC class I and MHC class II epitopes represents a promising approach to increase specific T cell immunity against cancer with clear clinical effects in patients. Without proper adjuvants peptides are poorly immunogenic. The current project focuses on the development of immmunostimulatory biodegradable (nano) particles as a delivery strategy to increase the immunogenicity of peptide antigens. These insights will be used for developing a potent particulate delivery system to improve the efficacy of peptide-based cancer vaccines which are already tested in the clinic. For this project we are looking for two PhD students, one of which will work at the LACDR, the other will be positioned at the LUMC.
Requirements
Required education/skills:University Graduate
Your profile
You hold a master degree in (bio)pharmaceutical sciences or biochemistry. You want to work at the interface of several biomedical/pharmaceutical disciplines and you have a keen interest in immunology.
You are highly motivated and you have excellent communication skills, including a good level of written and spoken English. You are flexible and able to work both independently and in a team.
Job type: Research / Advising
Workfield(s):
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Natural Sciences)
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Health)
Organization
Leiden University
Faculty of Mathematics and Natural Sciences
Conditions of employment
Employment basis: Temporary for specified period
Duration of the contract: 4 years
Maximum hours per week: 38
Additional conditions of employment:
What we offer
You will be employed on the basis of a 36-hour week. Appointment is for four years. Your salary will depend on your qualifications and experience, with a maximum of € 2,519 gross per month based on a full time position (scale for PhD students of the Collective Labour Agreement for Dutch Universities).
Additional Information
Additional information can be obtained through one of the following links:
You can apply for this job before 01-05-2008 (dd-mm-yyyy) by sending your application to:
Faculteit der Wiskunde en Natuurwetenschappen
Einsteinwegweg 55
J.C.M. van Gent-van Dorp
Postbus 9502
2300 RA Leiden
Nederland
E-mail: c.van.gent@lacdr.leidenuniv.nl
When applying for this job always mention the vacancynumber 8-084.
Leiden, 2300 RA (The Netherlands), 38 hours per week
Job description
Function title: Ph.D. Student
For a project entitled: "Improved delivery systems for efficacious peptide-based vaccines for immunotherapy of cancer"
The project
The Division of Drug Delivery Technology of the Leiden/Amsterdam center for Drug Research (LACDR), Leiden University and the Department of Clinical Pharmacy & Toxicology of the Leiden University Medical Center (LUMC) are joined together in an ambitious project to further develop vaccine-based immunotherapy of cancer.
Vaccination with synthetic peptides covering MHC class I and MHC class II epitopes represents a promising approach to increase specific T cell immunity against cancer with clear clinical effects in patients. Without proper adjuvants peptides are poorly immunogenic. The current project focuses on the development of immmunostimulatory biodegradable (nano) particles as a delivery strategy to increase the immunogenicity of peptide antigens. These insights will be used for developing a potent particulate delivery system to improve the efficacy of peptide-based cancer vaccines which are already tested in the clinic. For this project we are looking for two PhD students, one of which will work at the LACDR, the other will be positioned at the LUMC.
Requirements
Required education/skills:University Graduate
Your profile
You hold a master degree in (bio)pharmaceutical sciences or biochemistry. You want to work at the interface of several biomedical/pharmaceutical disciplines and you have a keen interest in immunology.
You are highly motivated and you have excellent communication skills, including a good level of written and spoken English. You are flexible and able to work both independently and in a team.
Job type: Research / Advising
Workfield(s):
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Natural Sciences)
- Research trainees, non-tenured lecturers, researchers(Scientific discipline: Health)
Organization
Leiden University
Faculty of Mathematics and Natural Sciences
Conditions of employment
Employment basis: Temporary for specified period
Duration of the contract: 4 years
Maximum hours per week: 38
Additional conditions of employment:
What we offer
You will be employed on the basis of a 36-hour week. Appointment is for four years. Your salary will depend on your qualifications and experience, with a maximum of € 2,519 gross per month based on a full time position (scale for PhD students of the Collective Labour Agreement for Dutch Universities).
Additional Information
Additional information can be obtained through one of the following links:
- About the organization (http://www.leiden.edu/)
- About the department (http://www.science.leidenuniv.nl/e/)
- About the function (http://www.vacatures.leidenuniv.nl/index.php3?m=1&c=1775)
You can apply for this job before 01-05-2008 (dd-mm-yyyy) by sending your application to:
Faculteit der Wiskunde en Natuurwetenschappen
Einsteinwegweg 55
J.C.M. van Gent-van Dorp
Postbus 9502
2300 RA Leiden
Nederland
E-mail: c.van.gent@lacdr.leidenuniv.nl
When applying for this job always mention the vacancynumber 8-084.
