University of Amsterdam The Academic Centre for Dentistry in Amsterdam (ACTA)
Amsterdam, 1066 EA (Noord-Holland), 38 hours per week
Job description
Salivary gland tumors are a very heterogeneous group of tumors comprising more than 40 subtypes, mostly variant adenocarcinomas. Therefore, accurate diagnosis, therapy and prognosis of these tumors is complicated. Adenocarcinomas of the breast and the gastrointestinal tract are characterized by altered expression and glycosylation of mucins with concomitant cellular and humoral immune responses. This has led to immunotherapeutical clinical trials aiming at stimulating the immune reactivity against these types of tumors. This project aims to gain insight in mucin expression and glycosylation patterns of salivary gland carcinomas. In addition, we will investigate whether changes in composition and glycosylation of mucins in salivary gland tumors are reflected in the secreted saliva, with possible application as non-invasive screening for diagnostics of salivary gland tumors. Additional candidate tumor markers may emerge, which will be further validated by studying their presence in embedded archival tissues.
Requirements
Required education/skills:University Graduate
We are looking for candidates with a master's degree in biomedical sciences and outstanding experimental skills motivated to improve patient care. Experience with immunohistochemistry, biochemical and molecular techniques is an advantage.
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Health)
Organization
University of Amsterdam
The Academic Centre for Dentistry in Amsterdam (ACTA)
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
ACTA comprises the combined Faculties of Dentistry of the University of Amsterdam and the VU University Amsterdam.
The Research Institute ACTA
Research at ACTA focuses on the study of health and diseases of the oral hard and soft tissues. Beside infectious diseases like dental caries and periodontal inflammatory processes, attention is paid to diseases of salivary glands and oral mucosa. It is the general aim to improve strategies for diagnosis, prevention and treatment of oral diseases.
The Research Institute ACTA has granted a multidisciplinary project on "The possible diagnostic role of mucin expression in tissue and saliva in patients with a salivary gland tumor", resulting from the synergy from the cooperative effort and expertise from the department of Oral Biochemistry and the department of Maxillofacial Surgery/Oral Pathology.
Conditions of employment
Estimated maximum salary per month: eur 2000 - 2500
Employment basis: Temporary for specified period
Duration of the contract: see below
Maximum hours per week: 38
Additional conditions of employment:
The appointment will be initially for one year. If the results are successful the appointed period will be prolonged by three years. The purpose is to complete a PhD-thesis by the end of the fourth year. You can visit our website www.ACTA.nl for a review of working conditions at ACTA.
Salary
Gross monthly salary starts at € 2.000,- in the first year and increases to € 2.558,- in the last year of the appointment, based on a fulltime employment.
Additional Information
Additional information about the vacancy can be obtained from:
Mw. Prof. Dr. E. Bloemena, pathologist, Oral Pathology
Telephone number: 31 (0)20 4444014
E-mail address: E.Bloemena@VUmc.nl
Or Prof. Dr. E.C.I. Veerman, Oral Biochemistry
Telephone number: 31 (0)20 4448672
E-mail address: ECI.Veerman@VUmc.nl
Or additional information can be obtained through one of the following links:
You can apply for this job before 05-07-2008 (dd-mm-yyyy) by sending your application to:
ACTA
Yvon de Vries
Louwesweg 1
1066 EA Amsterdam
the Netherlands
E-mail: y.de.vries@acta.nl
When applying for this job always mention the vacancynumber AT 08-11009.
Job description
Salivary gland tumors are a very heterogeneous group of tumors comprising more than 40 subtypes, mostly variant adenocarcinomas. Therefore, accurate diagnosis, therapy and prognosis of these tumors is complicated. Adenocarcinomas of the breast and the gastrointestinal tract are characterized by altered expression and glycosylation of mucins with concomitant cellular and humoral immune responses. This has led to immunotherapeutical clinical trials aiming at stimulating the immune reactivity against these types of tumors. This project aims to gain insight in mucin expression and glycosylation patterns of salivary gland carcinomas. In addition, we will investigate whether changes in composition and glycosylation of mucins in salivary gland tumors are reflected in the secreted saliva, with possible application as non-invasive screening for diagnostics of salivary gland tumors. Additional candidate tumor markers may emerge, which will be further validated by studying their presence in embedded archival tissues.
Requirements
Required education/skills:University Graduate
We are looking for candidates with a master's degree in biomedical sciences and outstanding experimental skills motivated to improve patient care. Experience with immunohistochemistry, biochemical and molecular techniques is an advantage.
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Health)
Organization
University of Amsterdam
The Academic Centre for Dentistry in Amsterdam (ACTA)
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
ACTA comprises the combined Faculties of Dentistry of the University of Amsterdam and the VU University Amsterdam.
The Research Institute ACTA
Research at ACTA focuses on the study of health and diseases of the oral hard and soft tissues. Beside infectious diseases like dental caries and periodontal inflammatory processes, attention is paid to diseases of salivary glands and oral mucosa. It is the general aim to improve strategies for diagnosis, prevention and treatment of oral diseases.
The Research Institute ACTA has granted a multidisciplinary project on "The possible diagnostic role of mucin expression in tissue and saliva in patients with a salivary gland tumor", resulting from the synergy from the cooperative effort and expertise from the department of Oral Biochemistry and the department of Maxillofacial Surgery/Oral Pathology.
Conditions of employment
Estimated maximum salary per month: eur 2000 - 2500
Employment basis: Temporary for specified period
Duration of the contract: see below
Maximum hours per week: 38
Additional conditions of employment:
The appointment will be initially for one year. If the results are successful the appointed period will be prolonged by three years. The purpose is to complete a PhD-thesis by the end of the fourth year. You can visit our website www.ACTA.nl for a review of working conditions at ACTA.
Salary
Gross monthly salary starts at € 2.000,- in the first year and increases to € 2.558,- in the last year of the appointment, based on a fulltime employment.
Additional Information
Additional information about the vacancy can be obtained from:
Mw. Prof. Dr. E. Bloemena, pathologist, Oral Pathology
Telephone number: 31 (0)20 4444014
E-mail address: E.Bloemena@VUmc.nl
Or Prof. Dr. E.C.I. Veerman, Oral Biochemistry
Telephone number: 31 (0)20 4448672
E-mail address: ECI.Veerman@VUmc.nl
Or additional information can be obtained through one of the following links:
- About the organization (http://www.uva.nl/start.cfm/la=en/th=main)
- About the department (http://www.acta.nl/english/index.cfm)
- About the function (http://www.uva.nl/vacatures/vacatures.cfm/5D30FA83-1321-B0BE-A4793CE4FC78F6CA)
You can apply for this job before 05-07-2008 (dd-mm-yyyy) by sending your application to:
ACTA
Yvon de Vries
Louwesweg 1
1066 EA Amsterdam
the Netherlands
E-mail: y.de.vries@acta.nl
When applying for this job always mention the vacancynumber AT 08-11009.
