University of Amsterdam Academic Centre for Dentistry in Amsterdam (ACTA)
Amsterdam, 1066 EA (Noord-Holland), 38 hours per week
Job description
With regard to a research project funded by the "Academic Centre for Dentistry Amsterdam" in the area of bone regeneration with adipose stem cells, growth factors, and calcium phosphate carrier for human sinus floor elevation in oral surgery, there is a vacancy for a PhD student at the "Vrije Universiteit".
PhD student Bone Regeneration and Stem Cells in Oral Surgery (1.0 FTE).
One of the limiting factors for placement of dental implants in the lateral maxilla is insufficient alveolar bone height. For more than 25 years these cases are treated with internal maxillary sinus floor augmentation to allow implant surgery (sinus floor elevation). Autologous bone is the golden standard, but harvesting bone has the disadvantage of a second surgical site. Therefore bone substitutes are needed that provide comparable results. The current bone substitutes have the disadvantage of slow bone ingrowth. If grafting with bone substitutes (Calcium Phosphates) is indicated, then sinus floor elevation is favorable, since the bone substitute is surrounded by vital bone. Earlier attempts with addition of growth factors in the sinus floor model were only partially successful and unpredictable, since only low numbers of stem cells were present at the surgical site. The hypothesis is that growth factor-treated stem cells seeded on calcium phosphate carrier will greatlly improve sinus floor elevation in oral surgery. This study is the first to use adipose stem cells for bone regeneration, and will lead to new insights in oral bone regeneration using bone substitutes.
Work environment
The PhD student will perform the work mainly at the Academic Center of Dentistry Amsterdam (ACTA), Vrije Universiteit, in the Departments of Oral and Maxillofacial Surgery and Oral Cell Biology.
Requirements
Required education/skills:University Graduate
Graduated (MSc) in dentistry, (medical) biology, biomedical medicine, biomedical technology, or comparable.
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Health)
Organization
University of Amsterdam
Academic Centre for Dentistry in Amsterdam (ACTA)
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
ACTA comprises the combined Faculties of Dentistry of the University of Amsterdam and the VU University Amsterdam.
Conditions of employment
Estimated maximum salary per month: eur 2000 - 2500
Employment basis: Temporary for specified period
Duration of the contract: The contract of employment will be for a period of 4 years.
Maximum hours per week: 38
Additional conditions of employment:
The contract of employment will be for a period of 4 years. It concerns a 100% employment. The salary is € 2.000,- during the first year, increasing to € 2.558,- gross per month during the fourth year, with a full-time contract of employment.
Additional Information
Additional information about the vacancy can be obtained from:
Prof. Dr. Jenneke Klein Nulend
Telephone number: 31 (0)20 44 48660
E-mail address: j.kleinnulend@vumc.nl
Or Prof. Dr. Chris ten Bruggenkate
Telephone number: 31 (0)20-4441030
E-mail address: chr.bruggenkate@vumc.nl
Or additional information can be obtained through one of the following links:
You can apply for this job before 05-07-2008 (dd-mm-yyyy) by sending your application to:
ACTA
Yvon de Vries
Louwesweg 1
1066 EA Amsterdam
the Netherlands
E-mail: y.de.vries@acta.nl
When applying for this job always mention the vacancynumber AT 08-11010.
Job description
With regard to a research project funded by the "Academic Centre for Dentistry Amsterdam" in the area of bone regeneration with adipose stem cells, growth factors, and calcium phosphate carrier for human sinus floor elevation in oral surgery, there is a vacancy for a PhD student at the "Vrije Universiteit".
PhD student Bone Regeneration and Stem Cells in Oral Surgery (1.0 FTE).
One of the limiting factors for placement of dental implants in the lateral maxilla is insufficient alveolar bone height. For more than 25 years these cases are treated with internal maxillary sinus floor augmentation to allow implant surgery (sinus floor elevation). Autologous bone is the golden standard, but harvesting bone has the disadvantage of a second surgical site. Therefore bone substitutes are needed that provide comparable results. The current bone substitutes have the disadvantage of slow bone ingrowth. If grafting with bone substitutes (Calcium Phosphates) is indicated, then sinus floor elevation is favorable, since the bone substitute is surrounded by vital bone. Earlier attempts with addition of growth factors in the sinus floor model were only partially successful and unpredictable, since only low numbers of stem cells were present at the surgical site. The hypothesis is that growth factor-treated stem cells seeded on calcium phosphate carrier will greatlly improve sinus floor elevation in oral surgery. This study is the first to use adipose stem cells for bone regeneration, and will lead to new insights in oral bone regeneration using bone substitutes.
Work environment
The PhD student will perform the work mainly at the Academic Center of Dentistry Amsterdam (ACTA), Vrije Universiteit, in the Departments of Oral and Maxillofacial Surgery and Oral Cell Biology.
Requirements
Required education/skills:University Graduate
Graduated (MSc) in dentistry, (medical) biology, biomedical medicine, biomedical technology, or comparable.
Job type: Research / Advising
Workfield(s):
- Teaching & Research(Scientific discipline: Health)
Organization
University of Amsterdam
Academic Centre for Dentistry in Amsterdam (ACTA)
The University of Amsterdam (UvA) is a university with an internationally acclaimed profile, located at the heart of the Dutch capital. As well as a world center for business and research, Amsterdam is a hub of cultural and media activities. The University of Amsterdam is a member of the League of European Research Universities.
ACTA comprises the combined Faculties of Dentistry of the University of Amsterdam and the VU University Amsterdam.
Conditions of employment
Estimated maximum salary per month: eur 2000 - 2500
Employment basis: Temporary for specified period
Duration of the contract: The contract of employment will be for a period of 4 years.
Maximum hours per week: 38
Additional conditions of employment:
The contract of employment will be for a period of 4 years. It concerns a 100% employment. The salary is € 2.000,- during the first year, increasing to € 2.558,- gross per month during the fourth year, with a full-time contract of employment.
Additional Information
Additional information about the vacancy can be obtained from:
Prof. Dr. Jenneke Klein Nulend
Telephone number: 31 (0)20 44 48660
E-mail address: j.kleinnulend@vumc.nl
Or Prof. Dr. Chris ten Bruggenkate
Telephone number: 31 (0)20-4441030
E-mail address: chr.bruggenkate@vumc.nl
Or additional information can be obtained through one of the following links:
- About the organization (http://www.uva.nl/start.cfm/la=en/th=main)
- About the department (http://www.acta.nl/english/index.cfm)
- About the function (http://www.uva.nl/vacatures/vacatures.cfm/5D465957-1321-B0BE-680C43B8744DC2A8)
You can apply for this job before 05-07-2008 (dd-mm-yyyy) by sending your application to:
ACTA
Yvon de Vries
Louwesweg 1
1066 EA Amsterdam
the Netherlands
E-mail: y.de.vries@acta.nl
When applying for this job always mention the vacancynumber AT 08-11010.
